Leila Najd Hassan Bonab
MSc, Cellular and Molecular, 2017; Royan Institute (Science and Culture)
PhD candidate of Molecular Genetics
Cell Phone: +989102006467
Email: Leila_nhb26@yahoo.com
Background
I was interested in experimental science from elementary school. I started my university education in biology. Then I started teaching biology in high school. I got MSc degree in cellular and molecular by focusing in designing molecular kit for genotyping Apolipoprotein E polymorphisms. Furthermore, I passed some advanced courses of Computer science and Biology such as bioinformatics, genetic (GWAS, NGS).
Technical skills and Genetics Laboratory
Kariminejad - Najmabadi Pathology & Genetics Center
Research Institute for Endocrine Sciences Shahid Beheshti University of Medical Sciences Tehran, Iran
• Expert technician in genetic lab with full experience on DNA extraction and banking, PCR based test and Electrophoresis of nucleic acids
• Designing of primers for different PCR based methods such as tetra-ARMS PCR primers
• Performing qualitative Polymerase Chain Reaction (PCR) techniques
• Providing PCR troubleshooting protocols
• Teaching the laboratory techniques and principles of working with laboratory equipment to new researchers
• Troubleshooting researchers' technical issues
• Analyzing the research outputs
• Familiar with data extraction of ONLINE DATABASES and SITES:
• experience on annotation and analyzing of Whole Exome Sequencing, Whole Exom Sequencing and genomic Chip data by: SAM tools, BAM tools, VCF tools, Plink, IGV
Thesis Title:
Designing a molecular kit for genotyping Apolipoprotein E polymorphisms by Tetra-ARMS PCR
Publications
1. Najd Hassan Bonab, Leila, Maryam Moazzam-Jazi, Reyhaneh-Sadat Miri Moosavi, Mohammad-Sadegh Fallah, Hossein Lanjanian, Sajedeh Masjoudi, and Maryam S. Daneshpour. "Low HDL concentration in rs2048327-G carriers can predispose men to develop coronary heart disease: Tehran Cardiometabolic genetic study (TCGS)." Gene 778 (2021): 145485.
2. Javanrouh Givi, N., Najd Hassan Bonab, L., Barzin, M. et al. The joint effect of PPARG upstream genetic variation in association with long-term persistent obesity: Tehran cardio-metabolic genetic study (TCGS). Eat Weight Disord (2021). https://doi.org/10.1007/s40519-020-01063-7
3. Moazzam-Jazi, M., Najd Hassan Bonab, L., Zahedi, A.S. et al. High genetic burden of type 2 diabetes can promote the high prevalence of disease: a longitudinal cohort study in Iran. Sci Rep 10, 14006 (2020). https://doi.org/10.1038/s41598-020-70725-4
4. Yari M, Najd Hassan Bonab L, Ahmadi R. Study of the effects of orchiectomy and testosterone and estradiol administration on lipids profile in male rats. J Shahid Sadoughi Uni Med Sci 2019; 27(4): 1415-25
Presentation and Conference Proceeding
Oral
"Testosterone, KATP Channels Openers or Blocker and Insulin Sensitivity"
(Istanbul, Turkey, 27-28 Sep 2019)
National Patent:
Designing a molecular kit for genotyping Apolipoprotein E polymorphisms by Tetra-ARMS PCR
Books:
• Cultivating Cell & Tissue
• Cell Culture Basics
Honors:
• Best paper of the International Conference of chemical, Environmental and Biomedical Sciences (ICCEBS20)-Turkey
• Selected as the top graduated student (M.Sc.), University of Science and Culture
• Second rank in Startup Biology Competition (Al-Zahra University)
Conferences:
• 17th C-HPP Symposium, Royan Research Institute
• 3rd International Congress of Iranian Personal Medicine
• Systematic Review / Meta-Analysis Articles
Education Courses:
• Application of Next generation Sequencing in clinical Diagnosis
• Concept of genome wide association studies and their importance
• Introduction to DNA and Protein Databases (summer school)
• Bioinformatics, Linux and shell script
• clinical genomics and NGS ، ESHG
• Preliminary and Advanced Research Methodology
• Article Writing
• Programming with R
• Peer review for scientific articles
Computer skills
Statistical Software
• Competent with most of Microsoft Office programmers; good knowledge about HTML, Windows, Linux.
• Programing: AWK and Bash (Advance)
• Some software for NGS study like as Samtools, Bam tools…
• R / RStudio
• SPSS
• Hirerachical clustering
Genetic Software
• PLINK
• PROGENY
• GeneRunner
• Haploview
• SNPAnalyzer
• R genetic packages
Other
• Endnote
• Mendeley reference manager
• Office ( word, excel, PowerPoint, access, Visio)
Language
• English ( fluent)
• Turkish (fluent)
Conferences:
• 17th C-HPP Symposium, Royan Research Institute
• 3rd International Congress of Iranian Personal Medicine
• Systematic Review / Meta-Analysis Articles
Education Courses:
• Application of Next generation sequencing in clinical Diagnosis
• Concept of genome wide association studies and their importance
• Introduction to DNA and Protein Databases (summer school)
• Bioinformatics, Linux and shell script
• Clinical genomics and NGS ، ESHG
• Preliminary and Advanced Research Methodology
• Article Writing
• Programming with R
• Peer review for scientific articles